Eravacycline

The Basics

What is Eravacycline?

A parenterally administered antibiotic used to treat moderate-to-severe intraabdominal infections due to susceptible organisms.

Brand names for Eravacycline

N/A

How Eravacycline is classified

Anti-Infective Agents, Antibacterial Agents, Tetracyclines

Eravacycline During Pregnancy

Eravacycline pregnancy category

Category N/ANote that the FDA has deprecated the use of pregnancy categories, so for some medications, this information isn’t available. We still think it’s useful to list historical info, however, given what a common proxy this has been in the past.

What we know about taking Eravacycline while pregnant

N/A

Taking Eravacycline While Breastfeeding

What are recommendations for lactation if you're taking Eravacycline?

Eravacycline is a tetracycline antibiotic. A number of reviews have stated that tetracyclines are contraindicated during breastfeeding because of possible staining of infants’ dental enamel or bone deposition of tetracyclines. However, a close examination of available literature indicates that there is not likely to be harm in short-term use of a eravacycline during lactation because the drug is 79 to 90% bound to plasma proteins, so milk levels are likely low and absorption by the infant is inhibited by the calcium in breastmilk. Short-term use of eravacycline acceptable in nursing mothers. As a theoretical precaution, avoid prolonged or repeat courses during nursing. Monitor the infant for rash and for possible effects on the gastrointestinal flora, such as diarrhea or candidiasis (thrush, diaper rash).

Maternal / infant drug levels

Eravacycline is a tetracycline antibiotic. A number of reviews have stated that tetracyclines are contraindicated during breastfeeding because of possible staining of infants’ dental enamel or bone deposition of tetracyclines. However, a close examination of available literature indicates that there is not likely to be harm in short-term use of a eravacycline during lactation because the drug is 79 to 90% bound to plasma proteins, so milk levels are likely low and absorption by the infant is inhibited by the calcium in breastmilk. Short-term use of eravacycline acceptable in nursing mothers. As a theoretical precaution, avoid prolonged or repeat courses during nursing. Monitor the infant for rash and for possible effects on the gastrointestinal flora, such as diarrhea or candidiasis (thrush, diaper rash).

Possible effects of Eravacycline on milk supply

Relevant published information was not found as of the revision date.

Possible alternatives to Eravacycline

None listed