The Basics
What is Sirolimus?
Used in combination with other medications to prevent rejection of kidney transplants.
Brand names for Sirolimus
Rapamune
How Sirolimus is classified
Immunosuppressive Agents
Sirolimus During Pregnancy
Sirolimus pregnancy category
Category CNote that the FDA has deprecated the use of pregnancy categories, so for some medications, this information isn’t available. We still think it’s useful to list historical info, however, given what a common proxy this has been in the past.
What we know about taking Sirolimus while pregnant
N/A
Taking Sirolimus While Breastfeeding
What are recommendations for lactation if you're taking Sirolimus?
Because almost no information is available on the use of sirolimus during breastfeeding, an alternate drug may be preferred, especially while nursing a newborn or preterm infant.
Maternal / infant drug levels
Because almost no information is available on the use of sirolimus during breastfeeding, an alternate drug may be preferred, especially while nursing a newborn or preterm infant.
Possible effects of Sirolimus on milk supply
Relevant published information was not found as of the revision date.
Possible alternatives to Sirolimus
Azathioprine, Cyclosporine, Tacrolimus.
List of References
Lactation sources: Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK501922/1. Bramham K, Chusney G, Lee J et al. Breastfeeding and tacrolimus: Serial monitoring in breast-fed and bottle-fed infants. Clin J Am Soc Nephrol. 2013;8:563-7. PMID: 23349333
Disclaimer: This material is provided for educational purposes only and is not intended for medical advice, diagnosis, or treatment. Consult your healthcare provider with any questions.
