The Basics
What is Coagulation Factor IX?
Used to prevent or control bleeding in people with little or no factor IX (due to hemophilia B, Christmas disease).
Brand names for Coagulation Factor IX
Alprolix
How Coagulation Factor IX is classified
Blood Coagulation Factors, Coagulants
Coagulation Factor IX During Pregnancy
Coagulation Factor IX pregnancy category
Category CNote that the FDA has deprecated the use of pregnancy categories, so for some medications, this information isn’t available. We still think it’s useful to list historical info, however, given what a common proxy this has been in the past.
What we know about taking Coagulation Factor IX while pregnant
Animal reproductive studies have not been conducted with ALPROLIX‚Ñ¢. It is also not known whether ALPROLIX‚Ñ¢ can cause fetal harm when administered to a pregnant woman or can affect reproduction capacity. ALPROLIX‚Ñ¢ should be given to a pregnant woman only if clearly needed.
Taking Coagulation Factor IX While Breastfeeding
What are recommendations for lactation if you're taking Coagulation Factor IX?
No information is available on the clinical use of coagulation factor IX during breastfeeding. Because it is a large protein molecule, the amount in milk is likely to be very low and absorption is unlikely because it is probably destroyed in the infant’s gastrointestinal tract. Until more data become available, coagulation factor IX should be used with caution during breastfeeding, especially while nursing a newborn or preterm infant.
Maternal / infant drug levels
No information is available on the clinical use of coagulation factor IX during breastfeeding. Because it is a large protein molecule, the amount in milk is likely to be very low and absorption is unlikely because it is probably destroyed in the infant’s gastrointestinal tract. Until more data become available, coagulation factor IX should be used with caution during breastfeeding, especially while nursing a newborn or preterm infant.
Possible effects of Coagulation Factor IX on milk supply
Relevant published information was not found as of the revision date.
Possible alternatives to Coagulation Factor IX
None listed
List of References
Lactation sources: Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK501922/None listed
Disclaimer: This material is provided for educational purposes only and is not intended for medical advice, diagnosis, or treatment. Consult your healthcare provider with any questions.
